Signs of an allergic reaction, like rash; Change in color of urine or stool to blue or green. Talk with your doctor. Using methylene blue with any of the following medicines is usually not recommended, but may be required in some cases. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Some drugs may have another patient information leaflet. This medicine must not be given into the spine. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Methylene blue may cause dizziness, confusion, or trouble in seeing clearly. Call your doctor for medical The results of some tests may be affected by methylene blue. Avoid sunlamps and tanning beds. Throw away unused or expired drugs. This is a decision you and your doctor will make. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. Methylene blue, also known as methylthioninium chloride, is a medication and dye. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Last updated on Oct 8, 2020. Methylene blue is a monoamine oxidase inhibitor (MAOI) that is used to combat depression and anxiety. We comply with the HONcode standard for trustworthy health information -. Do not start, stop, or change the dose of Safety and efficacy have been established in pediatric patients. The presence of other medical problems may affect the use of methylene blue. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Make sure you know how you react to methylene blue before you drive, use machines, or do other jobs that require you to be alert or able to see well. If you have any questions about methylene blue, please talk We comply with the HONcode standard for trustworthy health information -. Use a sunscreen when you are outdoors. Before you have any medical tests, tell the doctor in charge that you are using methylene blue. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. Methylene blue may cause serious allergic reactions, including anaphylaxis. This is not a list of all drugs or health problems that interact with methylene blue. There may be drug take-back programs in your area. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Specifically, it is used to treat methemoglobin levels that are greater than 30% or in which there are symptoms despite oxygen therapy. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. A severe and sometimes deadly problem called serotonin syndrome may happen. Check blood pressure and heart rate as the doctor has told you. Have blood work checked as you have been told by the doctor. This condition occurs when the blood cannot deliver oxygen where it is needed in the body. The risk may be greater if you also take certain other drugs. This condition occurs when the blood cannot deliver oxygen where it is needed in the body. These side effects may go away during treatment as your body adjusts to the medicine. Medically reviewed by Drugs.com. For methylene blue, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to methylene blue or any other medicines. Methylene blue also acts as a monoamine oxidase inhibitor (MAOI) and is used in the treatment of depression and anxiety. Using methylene blue while you are pregnant can harm your unborn baby. If you are pregnant or you get pregnant while taking Be ready to tell or show what was Tell your Follow all instructions closely. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Although not all of these side effects may occur, if they do occur they may need medical attention. The symptoms of serotonin syndrome include mental changes (confusion, hyperactivity, memory problems), muscle twitching, excessive sweating, shivering or shaking, diarrhea, trouble with coordination, or fever.